Rat Strain Differences in the Ability to Disrupt Sensorimotor Gating Are Limited to the Dopaminergic System, Specific to Prepulse Inhibition, and Unrelated to Changes in Startle Am...

por Kinney, Gene G., Wilkinson, Lynn O., Saywell, Kay L., Tricklebank, Mark D.
Publicado en J Neurosci (1999)

Novel conformation-specific monoclonal antibodies against amyloidogenic forms of transthyretin

por Higaki, Jeffrey N, Chakrabartty, Avi, Galant, Natalie J, Hammerson, Bradley, Torres, Ronald, Salmans, Joshua, Barbour, Robin, Kinney, Gene G
Publicado en Orphanet J Rare Dis (2015)

Group III Metabotropic Glutamate Receptor-Mediated Modulation of the Striatopallidal Synapse

por Valenti, Ornella, Marino, Michael J., Wittmann, Marion, Lis, Edward, DiLella, Anthony G., Kinney, Gene G., Conn, P. Jeffrey
Publicado en J Neurosci (2003)

A bifunctional peptide, “peptope”, for pre-targeting antibody 7D8 to systemic amyloid deposits

por Wall, Jonathan S., Williams, Angela, Foster, James S., Martin, Emily B., Richey, Tina, Stuckey, Alan, Macy, Sallie, Zago, Wagner, Kinney, Gene G., Kennel, Stephen J.
Publicado en Amyloid (2017)

Neutralization of Soluble, Synaptotoxic Amyloid β Species by Antibodies Is Epitope Specific

por Zago, Wagner, Buttini, Manuel, Comery, Thomas A., Nishioka, Christopher, Gardai, Shyra J., Seubert, Peter, Games, Dora, Bard, Frédérique, Schenk, Dale, Kinney, Gene G.
Publicado en J Neurosci (2012)

The Glycine Transporter Type 1 Inhibitor N-[3-(4′-Fluorophenyl)-3-(4′-Phenylphenoxy)Propyl]Sarcosine Potentiates NMDA Receptor-Mediated Responses In Vivo and Produces an Antipsycho...

por Kinney, Gene G., Sur, Cyrille, Burno, Maryann, Mallorga, Pierre J., Williams, Jacinta B., Figueroa, David J., Wittmann, Marion, Lemaire, Wei, Conn, P. Jeffrey
Publicado en J Neurosci (2003)

First‐in‐human assessment of PRX002, an anti–α‐synuclein monoclonal antibody, in healthy volunteers

por Schenk, Dale B., Koller, Martin, Ness, Daniel K., Griffith, Sue G., Grundman, Michael, Zago, Wagner, Soto, Jay, Atiee, George, Ostrowitzki, Susanne, Kinney, Gene G.
Publicado en Mov Disord (2016)

2A4 binds soluble and insoluble light chain aggregates from AL amyloidosis patients and promotes clearance of amyloid deposits by phagocytosis (†)

por Renz, Mark, Torres, Ronald, Dolan, Philip J., Tam, Stephen J., Tapia, Jose R., Li, Lauri, Salmans, Joshua R., Barbour, Robin M., Shughrue, Paul J., Nijjar, Tarlochan, Schenk, Dale, Kinney, Gene G., Zago, Wagner
Publicado en Amyloid (2016)

First-in-Human Phase I/II Study of NEOD001 in Patients With Light Chain Amyloidosis and Persistent Organ Dysfunction

por Gertz, Morie A., Landau, Heather, Comenzo, Raymond L., Seldin, David, Weiss, Brendan, Zonder, Jeffrey, Merlini, Giampaolo, Schönland, Stefan, Walling, Jackie, Kinney, Gene G., Koller, Martin, Schenk, Dale B., Guthrie, Spencer D., Liedtke, Michaela
Publicado en J Clin Oncol (2016)

Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

por Marino, Michael J., Williams, David L., O'Brien, Julie A., Valenti, Ornella, McDonald, Terrence P., Clements, Michelle K., Wang, Ruiping, DiLella, Anthony G., Hess, J. Fred, Kinney, Gene G., Conn, P. Jeffrey
Publicado 2003

Inhibition of Calcineurin-mediated Endocytosis and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Prevents Amyloid β Oligomer-induced Synaptic Disruption

por Zhao, Wei-Qin, Santini, Francesca, Breese, Robert, Ross, Dave, Zhang, Xiaohua Douglas, Stone, David J., Ferrer, Marc, Townsend, Matthew, Wolfe, Abigail L., Seager, Matthew A., Kinney, Gene G., Shughrue, Paul J., Ray, William J.
Publicado 2010

Novel conformation-specific monoclonal antibodies against amyloidogenic forms of transthyretin

por Higaki, Jeffrey N., Chakrabartty, Avi, Galant, Natalie J., Hadley, Kevin C., Hammerson, Bradley, Nijjar, Tarlochan, Torres, Ronald, Tapia, Jose R., Salmans, Joshua, Barbour, Robin, Tam, Stephen J., Flanagan, Ken, Zago, Wagner, Kinney, Gene G.
Publicado en Amyloid (2016)

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

por De Felice, Fernanda G., Wu, Diana, Lambert, Mary P., Fernandez, Sara J., Velasco, Pauline T., Lacor, Pascale N., Bigio, Eileen H., Jerecic, Jasna, Acton, Paul J., Shughrue, Paul J., Chen-Dodson, Elizabeth, Kinney, Gene G., Klein, William L.
Publicado 2007

Acute γ-Secretase Inhibition of Nonhuman Primate CNS Shifts Amyloid Precursor Protein (APP) Metabolism from Amyloid-β Production to Alternative APP Fragments without Amyloid-β Rebo...

por Cook, Jacquelynn J., Wildsmith, Kristin R., Gilberto, David B., Holahan, Marie A., Kinney, Gene G., Mathers, Parker D., Michener, Maria S., Price, Eric A., Shearman, Mark S., Simon, Adam J., Wang, Jennifer X., Wu, Guoxin, Yarasheski, Kevin E., Bateman, Randall J.
Publicado 2010

Safety and Tolerability of Multiple Ascending Doses of PRX002/RG7935, an Anti–α-Synuclein Monoclonal Antibody, in Patients With Parkinson Disease: A Randomized Clinical Trial

por Jankovic, Joseph, Goodman, Ira, Safirstein, Beth, Marmon, Tonya K., Schenk, Dale B., Koller, Martin, Zago, Wagner, Ness, Daniel K., Griffith, Sue G., Grundman, Michael, Soto, Jay, Ostrowitzki, Susanne, Boess, Frank G., Martin-Facklam, Meret, Quinn, Joseph F., Isaacson, Stuart H., Omidvar, Omid, Ellenbogen, Aaron, Kinney, Gene G.
Publicado en JAMA Neurol (2018)

Amyloid-related imaging abnormalities (ARIA) in Alzheimer’s disease patients treated with bapineuzumab: A retrospective analysis

por Sperling, Reisa, Salloway, Stephen, Brooks, David J., Tampieri, Donatella, Barakos, Jerome, Fox, Nick C., Raskind, Murray, Sabbagh, Marwan, Honig, Lawrence S., Porsteinsson, Anton P., Lieberburg, Ivan, Arrighi, H. Michael, Morris, Kristen A., Lu, Yuan, Liu, Enchi, Gregg, Keith M., Brashear, Robert H., Kinney, Gene G., Black, Ronald, Grundman, Michael
Publicado 2012