Novel conformation-specific monoclonal antibodies against amyloidogenic forms of transthyretin

Introduction: Transthyretin amyloidosis (ATTR amyloidosis) is caused by the misfolding and deposition of the transthyretin (TTR) protein and results in progressive multi-organ dysfunction. TTR epitopes exposed by dissociation and misfolding are targets for immunotherapeutic antibodies. We developed...

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Опубликовано в: :Amyloid
Главные авторы: Higaki, Jeffrey N., Chakrabartty, Avi, Galant, Natalie J., Hadley, Kevin C., Hammerson, Bradley, Nijjar, Tarlochan, Torres, Ronald, Tapia, Jose R., Salmans, Joshua, Barbour, Robin, Tam, Stephen J., Flanagan, Ken, Zago, Wagner, Kinney, Gene G.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898150/
https://ncbi.nlm.nih.gov/pubmed/26981744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2016.1148025
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