2A4 binds soluble and insoluble light chain aggregates from AL amyloidosis patients and promotes clearance of amyloid deposits by phagocytosis (†)

Amyloid light chain (AL) amyloidosis is characterized by misfolded light chain (LC) (amyloid) deposition in various peripheral organs, leading to progressive dysfunction and death. There are no regulatory agency–approved treatments for AL amyloidosis, and none of the available standard of care appro...

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Bibliographische Detailangaben
Veröffentlicht in:Amyloid
Hauptverfasser: Renz, Mark, Torres, Ronald, Dolan, Philip J., Tam, Stephen J., Tapia, Jose R., Li, Lauri, Salmans, Joshua R., Barbour, Robin M., Shughrue, Paul J., Nijjar, Tarlochan, Schenk, Dale, Kinney, Gene G., Zago, Wagner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152553/
https://ncbi.nlm.nih.gov/pubmed/27494229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13506129.2016.1205974
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