2A4 binds soluble and insoluble light chain aggregates from AL amyloidosis patients and promotes clearance of amyloid deposits by phagocytosis (†)

Amyloid light chain (AL) amyloidosis is characterized by misfolded light chain (LC) (amyloid) deposition in various peripheral organs, leading to progressive dysfunction and death. There are no regulatory agency–approved treatments for AL amyloidosis, and none of the available standard of care appro...

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Detalhes bibliográficos
Publicado no:Amyloid
Main Authors: Renz, Mark, Torres, Ronald, Dolan, Philip J., Tam, Stephen J., Tapia, Jose R., Li, Lauri, Salmans, Joshua R., Barbour, Robin M., Shughrue, Paul J., Nijjar, Tarlochan, Schenk, Dale, Kinney, Gene G., Zago, Wagner
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152553/
https://ncbi.nlm.nih.gov/pubmed/27494229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13506129.2016.1205974
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