Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

Parkinson's disease (PD) is a debilitating movement disorder that afflicts >1 million people in North America. Current treatments focused on dopamine-replacement strategies ultimately fail in most patients because of loss of efficacy and severe adverse effects that worsen as the disease prog...

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Hlavní autoři: Marino, Michael J., Williams, David L., O'Brien, Julie A., Valenti, Ornella, McDonald, Terrence P., Clements, Michelle K., Wang, Ruiping, DiLella, Anthony G., Hess, J. Fred, Kinney, Gene G., Conn, P. Jeffrey
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC263871/
https://ncbi.nlm.nih.gov/pubmed/14593202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835724100
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