Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

Parkinson's disease (PD) is a debilitating movement disorder that afflicts >1 million people in North America. Current treatments focused on dopamine-replacement strategies ultimately fail in most patients because of loss of efficacy and severe adverse effects that worsen as the disease prog...

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Главные авторы: Marino, Michael J., Williams, David L., O'Brien, Julie A., Valenti, Ornella, McDonald, Terrence P., Clements, Michelle K., Wang, Ruiping, DiLella, Anthony G., Hess, J. Fred, Kinney, Gene G., Conn, P. Jeffrey
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2003
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC263871/
https://ncbi.nlm.nih.gov/pubmed/14593202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835724100
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