Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

Alzheimer’s disease (AD) is characterized by presence of extracellular fibrillar Aβ in amyloid plaques, intraneuronal neurofibrillary tangles consisting of aggregated hyperphosphorylated tau and elevated brain levels of soluble Aβ oligomers (ADDLs). A major question is how these disparate facets of...

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Bibliografski detalji
Glavni autori: De Felice, Fernanda G., Wu, Diana, Lambert, Mary P., Fernandez, Sara J., Velasco, Pauline T., Lacor, Pascale N., Bigio, Eileen H., Jerecic, Jasna, Acton, Paul J., Shughrue, Paul J., Chen-Dodson, Elizabeth, Kinney, Gene G., Klein, William L.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142933/
https://ncbi.nlm.nih.gov/pubmed/17403556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.02.029
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