Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

Alzheimer’s disease (AD) is characterized by presence of extracellular fibrillar Aβ in amyloid plaques, intraneuronal neurofibrillary tangles consisting of aggregated hyperphosphorylated tau and elevated brain levels of soluble Aβ oligomers (ADDLs). A major question is how these disparate facets of...

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Detalhes bibliográficos
Main Authors: De Felice, Fernanda G., Wu, Diana, Lambert, Mary P., Fernandez, Sara J., Velasco, Pauline T., Lacor, Pascale N., Bigio, Eileen H., Jerecic, Jasna, Acton, Paul J., Shughrue, Paul J., Chen-Dodson, Elizabeth, Kinney, Gene G., Klein, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142933/
https://ncbi.nlm.nih.gov/pubmed/17403556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.02.029
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