Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

Alzheimer’s disease (AD) is characterized by presence of extracellular fibrillar Aβ in amyloid plaques, intraneuronal neurofibrillary tangles consisting of aggregated hyperphosphorylated tau and elevated brain levels of soluble Aβ oligomers (ADDLs). A major question is how these disparate facets of...

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Detaylı Bibliyografya
Asıl Yazarlar: De Felice, Fernanda G., Wu, Diana, Lambert, Mary P., Fernandez, Sara J., Velasco, Pauline T., Lacor, Pascale N., Bigio, Eileen H., Jerecic, Jasna, Acton, Paul J., Shughrue, Paul J., Chen-Dodson, Elizabeth, Kinney, Gene G., Klein, William L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142933/
https://ncbi.nlm.nih.gov/pubmed/17403556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.02.029
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