Reprogramming of Virus-specific T Cells into Leukemia-reactive T Cells Using T Cell Receptor Gene Transfer

Por Heemskerk, Mirjam H.M., Hoogeboom, Manja, Hagedoorn, Renate, Kester, Michel G.D., Willemze, Roel, Falkenburg, J.H. Frederik
Publicado em 2004

Successful generation of primary virus-specific and anti-tumor T-cell responses from the naïve donor T-cell repertoire is determined by the balance between antigen-specific precurs...

Por Jedema, Inge, van de Meent, Marian, Pots, Jeanette, Kester, Michel G.D., van der Beek, Martha T., Falkenburg, J.H. Frederik
Publicado em 2011

Retroviral transfer of human CD20 as a suicide gene for adoptive T-cell therapy

Por Griffioen, Marieke, van Egmond, Esther H.M., Kester, Michel G.D., Willemze, Roel, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado em 2009

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo

Por Thordardottir, Soley, Schaap, Nicolaas, Louer, Elja, Kester, Michel G. D., Falkenburg, J. H. Frederik, Jansen, Joop, Radstake, Timothy R. D., Hobo, Willemijn, Dolstra, Harry
Publicado no Oncoimmunology (2017)

High-Throughput Identification of Potential Minor Histocompatibility Antigens by MHC Tetramer-Based Screening: Feasibility and Limitations

Por Hombrink, Pleun, Hadrup, Sine R., Bakker, Arne, Kester, Michel G. D., Falkenburg, J. H. Frederik, von dem Borne, Peter A., Schumacher, Ton N. M., Heemskerk, Mirjam H. M.
Publicado em 2011

HSPVdb—the Human Short Peptide Variation Database for improved mass spectrometry-based detection of polymorphic HLA-ligands

Por Nijveen, Harm, Kester, Michel G. D., Hassan, Chopie, Viars, Aurélie, de Ru, Arnoud H., de Jager, Machiel, Falkenburg, J. H. Fred, Leunissen, Jack A. M., van Veelen, Peter A.
Publicado em 2010

A Polymorphism in the Splice Donor Site of ZNF419 Results in the Novel Renal Cell Carcinoma-Associated Minor Histocompatibility Antigen ZAPHIR

Por Broen, Kelly, Levenga, Henriette, Vos, Johanna, van Bergen, Kees, Fredrix, Hanny, Greupink-Draaisma, Annelies, Kester, Michel, Falkenburg, J. H. Frederik, de Mulder, Pieter, de Witte, Theo, Griffioen, Marieke, Dolstra, Harry
Publicado em 2011

Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes

Por Pinkse, Gabrielle G. M., Tysma, Odette H. M., Bergen, Cees A. M., Kester, Michel G. D., Ossendorp, Ferry, van Veelen, Peter A., Keymeulen, Bart, Pipeleers, Danny, Drijfhout, Jan W., Roep, Bart O.
Publicado em 2005

Identification of non-mutated neoantigens presented by TAP-deficient tumors

Por Marijt, Koen A., Blijleven, Laura, Verdegaal, Els M.E., Kester, Michel G., Kowalewski, Daniel J., Rammensee, Hans-Georg, Stevanović, Stefan, Heemskerk, Mirjam H.M., van der Burg, Sjoerd H., van Hall, Thorbald
Publicado no J Exp Med (2018)

Identification of 4 novel HLA-B*40:01 restricted minor histocompatibility antigens and their potential as targets for graft-versus-leukemia reactivity

Por Griffioen, Marieke, Honders, M. Willy, van der Meijden, Edith D., van Luxemburg-Heijs, Simone A.P., Lurvink, Ellie G.A., Kester, Michel G.D., van Bergen, Cornelis A.M., Falkenburg, J.H. Frederik
Publicado em 2012

The Human Leukocyte Antigen–presented Ligandome of B Lymphocytes

Por Hassan, Chopie, Kester, Michel G. D., de Ru, Arnoud H., Hombrink, Pleun, Drijfhout, Jan Wouter, Nijveen, Harm, Leunissen, Jack A. M., Heemskerk, Mirjam H. M., Falkenburg, J. H. Frederik, van Veelen, Peter A.
Publicado em 2013

Naturally Processed Non-canonical HLA-A*02:01 Presented Peptides

Por Hassan, Chopie, Chabrol, Eric, Jahn, Lorenz, Kester, Michel G. D., de Ru, Arnoud H., Drijfhout, Jan W., Rossjohn, Jamie, Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M., Gras, Stephanie, van Veelen, Peter A.
Publicado no J Biol Chem (2015)

Integrated whole genome and transcriptome analysis identified a therapeutic minor histocompatibility antigen encoded by an alternative ITGB2 transcript

Por Pont, Margot J, van der Lee, Dyantha, van der Meijden, Edith, van Bergen, Cornelis, Kester, Michel, Honders, Maria, Vermaat, Martijn, Eefting, Matthias, Marijt, Erik, Kielbasa, Szymon, 't Hoen, Peter-Bram, Falkenburg, Frederik, Griffioen, Marieke
Publicado no J Immunother Cancer (2015)

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer

Por Jahn, Lorenz, Hagedoorn, Renate S., van der Steen, Dirk M., Hombrink, Pleun, Kester, Michel G.D., Schoonakker, Marjolein P., de Ridder, Daniëlle, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado no Oncotarget (2016)

Generation of CD20-specific TCRs for TCR gene therapy of CD20(low) B-cell malignancies insusceptible to CD20-targeting antibodies

Por Jahn, Lorenz, van der Steen, Dirk M., Hagedoorn, Renate S., Hombrink, Pleun, Kester, Michel G.D., Schoonakker, Marjolein P., de Ridder, Daniëlle, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado no Oncotarget (2016)

A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia

Por Rijke, Björn de, van Horssen-Zoetbrood, Agnes, Beekman, Jeffrey M., Otterud, Britt, Maas, Frans, Woestenenk, Rob, Kester, Michel, Leppert, Mark, Schattenberg, Anton V., de Witte, Theo, van de Wiel-van Kemenade, Elly, Dolstra, Harry
Publicado em 2005

Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells

Por Kronenberg, Deborah, Knight, Robin R., Estorninho, Megan, Ellis, Richard J., Kester, Michel G., de Ru, Arnoud, Eichmann, Martin, Huang, Guo C., Powrie, Jake, Dayan, Colin M., Skowera, Ania, van Veelen, Peter A., Peakman, Mark
Publicado em 2012

Promiscuous Binding of Invariant Chain-Derived CLIP Peptide to Distinct HLA-I Molecules Revealed in Leukemic Cells

Por van Luijn, Marvin M., van de Loosdrecht, Arjan A., Lampen, Margit H., van Veelen, Peter A., Zevenbergen, Adri, Kester, Michel G. D., de Ru, Arnoud H., Ossenkoppele, Gert J., van Hall, Thorbald, van Ham, S. Marieke
Publicado em 2012

Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy

Por van der Waart, Anniek B., van de Weem, Noortje M. P., Maas, Frans, Kramer, Cynthia S. M., Kester, Michel G. D., Falkenburg, J. H. Frederik, Schaap, Nicolaas, Jansen, Joop H., van der Voort, Robbert, Gattinoni, Luca, Hobo, Willemijn, Dolstra, Harry
Publicado no Blood (2014)

Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8(+) T cells for adoptive immunotherapy

Por Mousset, Charlotte M., Hobo, Willemijn, Ji, Yun, Fredrix, Hanny, De Giorgi, Valeria, Allison, Robert D., Kester, Michel G. D., Falkenburg, J. H. Frederik, Schaap, Nicolaas P. M., Jansen, Joop H., Gattinoni, Luca, Dolstra, Harry, van der Waart, Anniek B.
Publicado no Oncoimmunology (2018)