A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies

Por Rosskopf, Sandra, Leitner, Judith, Paster, Wolfgang, Morton, Laura T., Hagedoorn, Renate S., Steinberger, Peter, Heemskerk, Mirjam H.M.
Publicado no Oncotarget (2018)

Extracellular Domains of CD8α and CD8ß Subunits Are Sufficient for HLA Class I Restricted Helper Functions of TCR-Engineered CD4(+) T Cells

Por van Loenen, Marleen M., Hagedoorn, Renate S., de Boer, Renate, Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Publicado em 2013

Reprogramming of Virus-specific T Cells into Leukemia-reactive T Cells Using T Cell Receptor Gene Transfer

Por Heemskerk, Mirjam H.M., Hoogeboom, Manja, Hagedoorn, Renate, Kester, Michel G.D., Willemze, Roel, Falkenburg, J.H. Frederik
Publicado em 2004

Induction of A. fumigatus-specific CD4-positive T cells in patients recovering from invasive aspergillosis

Por Jolink, Hetty, Hagedoorn, Renate S., Lagendijk, Ellen L., Drijfhout, Jan W., van Dissel, Jaap T., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado em 2014

Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies

Por van Loenen, Marleen M., de Boer, Renate, Hagedoorn, Renate S., van Egmond, Esther H.M., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado em 2011

Preclinical Strategies to Identify Off-Target Toxicity of High-Affinity TCRs

Por Bijen, Helena M., van der Steen, Dirk M., Hagedoorn, Renate S., Wouters, Anne K., Wooldridge, Linda, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado no Mol Ther (2018)

Mixed T cell receptor dimers harbor potentially harmful neoreactivity

Por van Loenen, Marleen M., de Boer, Renate, Amir, Avital L., Hagedoorn, Renate S., Volbeda, Gerdien L., Willemze, Roelof, van Rood, Johannes J., Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Publicado em 2010

PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy

Por Luk, Sietse J, van der Steen, Dirk M, Hagedoorn, Renate S, Jordanova, Ekaterina S, Schilham, Marco W, Bovée, Judith VMG, Cleven, Arjen HG, Falkenburg, JH Frederik, Szuhai, Karoly, Heemskerk, Mirjam HM
Publicado no Oncoimmunology (2018)

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer

Por Jahn, Lorenz, Hagedoorn, Renate S., van der Steen, Dirk M., Hombrink, Pleun, Kester, Michel G.D., Schoonakker, Marjolein P., de Ridder, Daniëlle, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado no Oncotarget (2016)

Generation of CD20-specific TCRs for TCR gene therapy of CD20(low) B-cell malignancies insusceptible to CD20-targeting antibodies

Por Jahn, Lorenz, van der Steen, Dirk M., Hagedoorn, Renate S., Hombrink, Pleun, Kester, Michel G.D., Schoonakker, Marjolein P., de Ridder, Daniëlle, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado no Oncotarget (2016)

PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma

Por Gezgin, Gülçin, Luk, Sietse J., Cao, Jinfeng, Dogrusöz, Mehmet, van der Steen, Dirk M., Hagedoorn, Renate S., Krijgsman, Daniëlle, van der Velden, Pieter A., Field, Matthew G., Luyten, Gregorius P. M., Szuhai, Karoly, Harbour, J. William, Jordanova, Ekaterina S., Heemskerk, Mirjam H. M., Jager, Martine J.
Publicado no JAMA Ophthalmol (2017)

Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia

Por van der Lee, Dyantha I., Reijmers, Rogier M., Honders, Maria W., Hagedoorn, Renate S., de Jong, Rob C.M., Kester, Michel G.D., van der Steen, Dirk M., de Ru, Arnoud H., Kweekel, Christiaan, Bijen, Helena M., Jedema, Inge, Veelken, Hendrik, van Veelen, Peter A., Heemskerk, Mirjam H.M., Falkenburg, J.H. Frederik, Griffioen, Marieke
Publicado no J Clin Invest (2019)