PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy

Synovial sarcoma expresses multiple cancer testis antigens that could potentially be targeted by T-cell receptor (TCR) gene therapy. In this study we investigated whether PRAME-TCR-gene therapy could be an effective treatment for synovial sarcoma by investigating the potential of PRAME-specific T-ce...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Luk, Sietse J, van der Steen, Dirk M, Hagedoorn, Renate S, Jordanova, Ekaterina S, Schilham, Marco W, Bovée, Judith VMG, Cleven, Arjen HG, Falkenburg, JH Frederik, Szuhai, Karoly, Heemskerk, Mirjam HM
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279314/
https://ncbi.nlm.nih.gov/pubmed/30524904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1507600
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