PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma

IMPORTANCE: Uveal melanoma (UM) is an intraocular primary malignant neoplasm that often gives rise to metastatic disease for which there are no effective therapies. A substantial proportion of UMs express the cancer-testis antigen PRAME (preferentially expressed antigen in melanoma), which can poten...

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Detaylı Bibliyografya
Yayımlandı:JAMA Ophthalmol
Asıl Yazarlar: Gezgin, Gülçin, Luk, Sietse J., Cao, Jinfeng, Dogrusöz, Mehmet, van der Steen, Dirk M., Hagedoorn, Renate S., Krijgsman, Daniëlle, van der Velden, Pieter A., Field, Matthew G., Luyten, Gregorius P. M., Szuhai, Karoly, Harbour, J. William, Jordanova, Ekaterina S., Heemskerk, Mirjam H. M., Jager, Martine J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509351/
https://ncbi.nlm.nih.gov/pubmed/28448663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2017.0729
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