PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma

IMPORTANCE: Uveal melanoma (UM) is an intraocular primary malignant neoplasm that often gives rise to metastatic disease for which there are no effective therapies. A substantial proportion of UMs express the cancer-testis antigen PRAME (preferentially expressed antigen in melanoma), which can poten...

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Publicado no:JAMA Ophthalmol
Main Authors: Gezgin, Gülçin, Luk, Sietse J., Cao, Jinfeng, Dogrusöz, Mehmet, van der Steen, Dirk M., Hagedoorn, Renate S., Krijgsman, Daniëlle, van der Velden, Pieter A., Field, Matthew G., Luyten, Gregorius P. M., Szuhai, Karoly, Harbour, J. William, Jordanova, Ekaterina S., Heemskerk, Mirjam H. M., Jager, Martine J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509351/
https://ncbi.nlm.nih.gov/pubmed/28448663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2017.0729
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