PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma

IMPORTANCE: Uveal melanoma (UM) is an intraocular primary malignant neoplasm that often gives rise to metastatic disease for which there are no effective therapies. A substantial proportion of UMs express the cancer-testis antigen PRAME (preferentially expressed antigen in melanoma), which can poten...

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書誌詳細
出版年:JAMA Ophthalmol
主要な著者: Gezgin, Gülçin, Luk, Sietse J., Cao, Jinfeng, Dogrusöz, Mehmet, van der Steen, Dirk M., Hagedoorn, Renate S., Krijgsman, Daniëlle, van der Velden, Pieter A., Field, Matthew G., Luyten, Gregorius P. M., Szuhai, Karoly, Harbour, J. William, Jordanova, Ekaterina S., Heemskerk, Mirjam H. M., Jager, Martine J.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509351/
https://ncbi.nlm.nih.gov/pubmed/28448663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2017.0729
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