Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment

Uveal melanoma (UM) is characterized by a number of genetic aberrations that follow a certain chronology and are tightly linked to tumor recurrence and survival. Loss of chromosome 3, bi-allelic loss of BAP1 expression, and gain in chromosome 8q have been associated with metastasis formation and dea...

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Dades bibliogràfiques
Publicat a:Cancer Immunol Immunother
Autors principals: Gezgin, Gülçin, Dogrusöz, Mehmet, van Essen, T. Huibertus, Kroes, Wilhelmina G. M., Luyten, Gregorius P. M., van der Velden, Pieter A., Walter, Vonn, Verdijk, Robert M., van Hall, Thorbald, van der Burg, Sjoerd H., Jager, Martine J.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2017
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489616/
https://ncbi.nlm.nih.gov/pubmed/28391358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-017-1991-1
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