Heterogeneity revealed by integrated genomic analysis uncovers a molecular switch in malignant uveal melanoma

Gene expression profiles as well as genomic imbalances are correlated with disease progression in uveal melanoma (UM). We integrated expression and genomic profiles to obtain insight into the oncogenic mechanisms in development and progression of UM. We used tumor tissue from 64 enucleated eyes of U...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: de Lange, Mark J., van Pelt, Sake I., Versluis, Mieke, Jordanova, Ekaterina S., Kroes, Wilma G.M., Ruivenkamp, Claudia, van der Burg, Sjoerd H., Luyten, Grégorius P.M., van Hall, Thorbald, Jager, Martine J., van der Velden, Pieter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741968/
https://ncbi.nlm.nih.gov/pubmed/26462151
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