Heterogeneity revealed by integrated genomic analysis uncovers a molecular switch in malignant uveal melanoma

Gene expression profiles as well as genomic imbalances are correlated with disease progression in uveal melanoma (UM). We integrated expression and genomic profiles to obtain insight into the oncogenic mechanisms in development and progression of UM. We used tumor tissue from 64 enucleated eyes of U...

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Udgivet i:Oncotarget
Main Authors: de Lange, Mark J., van Pelt, Sake I., Versluis, Mieke, Jordanova, Ekaterina S., Kroes, Wilma G.M., Ruivenkamp, Claudia, van der Burg, Sjoerd H., Luyten, Grégorius P.M., van Hall, Thorbald, Jager, Martine J., van der Velden, Pieter A.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741968/
https://ncbi.nlm.nih.gov/pubmed/26462151
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