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Digital PCR Validates 8q Dosage as Prognostic Tool in Uveal Melanoma
BACKGROUND: Uveal melanoma (UM) development and progression is correlated with specific molecular changes. Recurrent mutations in GNAQ and GNA11 initiate UM development while tumour progression is correlated with monosomy of chromosome 3 and gain of chromosome 8q. Hence, molecular analysis of UM is...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357379/ https://ncbi.nlm.nih.gov/pubmed/25764247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116371 |
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