Digital PCR Validates 8q Dosage as Prognostic Tool in Uveal Melanoma

BACKGROUND: Uveal melanoma (UM) development and progression is correlated with specific molecular changes. Recurrent mutations in GNAQ and GNA11 initiate UM development while tumour progression is correlated with monosomy of chromosome 3 and gain of chromosome 8q. Hence, molecular analysis of UM is...

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Udgivet i:PLoS One
Main Authors: Versluis, Mieke, de Lange, Mark J., van Pelt, Sake I., Ruivenkamp, Claudia A. L., Kroes, Wilma G. M., Cao, Jinfeng, Jager, Martine J., Luyten, Gre P. M., van der Velden, Pieter A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357379/
https://ncbi.nlm.nih.gov/pubmed/25764247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116371
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