Do GNAQ and GNA11 Differentially Affect Inflammation and HLA Expression in Uveal Melanoma?

Inflammation, characterized by high numbers of infiltrating leukocytes and a high HLA Class I expression, is associated with a bad prognosis in uveal melanoma (UM). We wondered whether mutations in GNA11 or GNAQ differentially affect inflammation and HLA expression, and thereby progression of the di...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: van Weeghel, Christiaan, Wierenga, Annemijn P. A., Versluis, Mieke, van Hall, Thorbald, van der Velden, Pieter A., Kroes, Wilma G. M., Pfeffer, Ulrich, Luyten, Gregorius P. M., Jager, Martine J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721447/
https://ncbi.nlm.nih.gov/pubmed/31394807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081127
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