Loss of BAP1 Is Associated with Upregulation of the NFkB Pathway and Increased HLA Class I Expression in Uveal Melanoma

One of the characteristics of prognostically infaust uveal melanoma (UM) is an inflammatory phenotype, which is characterized by high numbers of infiltrating T cells and macrophages, and a high HLA Class I expression. We wondered how this inflammation is regulated, and considered that one of the mos...

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Pubblicato in:Cancers (Basel)
Autori principali: Souri, Zahra, Wierenga, Annemijn P. A., van Weeghel, Christiaan, van der Velden, Pieter A., Kroes, Wilma G. M., Luyten, Gregorius P. M., van der Burg, Sjoerd H., Jochemsen, Aart G., Jager, Martine J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721427/
https://ncbi.nlm.nih.gov/pubmed/31382450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081102
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