PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy

Synovial sarcoma expresses multiple cancer testis antigens that could potentially be targeted by T-cell receptor (TCR) gene therapy. In this study we investigated whether PRAME-TCR-gene therapy could be an effective treatment for synovial sarcoma by investigating the potential of PRAME-specific T-ce...

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Bibliografski detalji
Izdano u:Oncoimmunology
Glavni autori: Luk, Sietse J, van der Steen, Dirk M, Hagedoorn, Renate S, Jordanova, Ekaterina S, Schilham, Marco W, Bovée, Judith VMG, Cleven, Arjen HG, Falkenburg, JH Frederik, Szuhai, Karoly, Heemskerk, Mirjam HM
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2018
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279314/
https://ncbi.nlm.nih.gov/pubmed/30524904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1507600
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