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Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies
To broaden the applicability of adoptive T-cell therapy for the treatment of hematologic malignancies, we aim to start a clinical trial using HA-1-TCR transferred virus-specific T cells. TCRs directed against the minor histocompatibility antigen (MiHA) HA-1 are good candidates for TCR gene transfer...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Ferrata Storti Foundation
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046283/ https://ncbi.nlm.nih.gov/pubmed/21109688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.025916 |
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