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Retroviral transfer of human CD20 as a suicide gene for adoptive T-cell therapy
The aim of adoptive T-cell therapy of cancer is to selectively confer immunity against tumor cells. Autoimmune side effects, however, remain a risk, emphasizing the relevance of a suicide mechanism allowing in vivo elimination of infused T cells. We investigated the use of human CD20 as suicide gene...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Ferrata Storti Foundation
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738728/ https://ncbi.nlm.nih.gov/pubmed/19734426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2008.001677 |
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