Promiscuous Binding of Invariant Chain-Derived CLIP Peptide to Distinct HLA-I Molecules Revealed in Leukemic Cells

Antigen presentation by HLA class I (HLA-I) and HLA class II (HLA-II) complexes is achieved by proteins that are specific for their respective processing pathway. The invariant chain (Ii)-derived peptide CLIP is required for HLA-II-mediated antigen presentation by stabilizing HLA-II molecules before...

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Detalhes bibliográficos
Main Authors: van Luijn, Marvin M., van de Loosdrecht, Arjan A., Lampen, Margit H., van Veelen, Peter A., Zevenbergen, Adri, Kester, Michel G. D., de Ru, Arnoud H., Ossenkoppele, Gert J., van Hall, Thorbald, van Ham, S. Marieke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338516/
https://ncbi.nlm.nih.gov/pubmed/22563374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034649
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