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Tumor immune escape in acute myeloid leukemia: Class II-associated invariant chain peptide expression as result of deficient antigen presentation

In this overview, we discuss the role of class II-associated invariant chain peptide (CLIP) in acute myeloid leukemia (AML), one of the few tumors expressing HLA class II. The clinical impact, function and regulation of CLIP expression on leukemic cells is addressed, indicating its potential as immu...

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Detalhes bibliográficos
Main Authors: van Luijn, Marvin M., Chamuleau, Martine E.D., Ossenkoppele, Gert J., van de Loosdrecht, Arjan A., Marieke van Ham, S.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376995/
https://ncbi.nlm.nih.gov/pubmed/22720245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18100
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