Tumor immune escape in acute myeloid leukemia: Class II-associated invariant chain peptide expression as result of deficient antigen presentation

In this overview, we discuss the role of class II-associated invariant chain peptide (CLIP) in acute myeloid leukemia (AML), one of the few tumors expressing HLA class II. The clinical impact, function and regulation of CLIP expression on leukemic cells is addressed, indicating its potential as immu...

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Auteurs principaux: van Luijn, Marvin M., Chamuleau, Martine E.D., Ossenkoppele, Gert J., van de Loosdrecht, Arjan A., Marieke van Ham, S.
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376995/
https://ncbi.nlm.nih.gov/pubmed/22720245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18100
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