Promiscuous Binding of Invariant Chain-Derived CLIP Peptide to Distinct HLA-I Molecules Revealed in Leukemic Cells

Antigen presentation by HLA class I (HLA-I) and HLA class II (HLA-II) complexes is achieved by proteins that are specific for their respective processing pathway. The invariant chain (Ii)-derived peptide CLIP is required for HLA-II-mediated antigen presentation by stabilizing HLA-II molecules before...

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Main Authors: van Luijn, Marvin M., van de Loosdrecht, Arjan A., Lampen, Margit H., van Veelen, Peter A., Zevenbergen, Adri, Kester, Michel G. D., de Ru, Arnoud H., Ossenkoppele, Gert J., van Hall, Thorbald, van Ham, S. Marieke
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338516/
https://ncbi.nlm.nih.gov/pubmed/22563374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034649
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