Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes

Type 1 diabetes is a T cell-mediated autoimmune disease, and insulin is an important target of the autoimmune response associated with β cell destruction. The mechanism of destruction is still unknown. Here, we provide evidence for CD8 T cell autoreactivity associated with recurrent autoimmunity and...

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Detalhes bibliográficos
Main Authors: Pinkse, Gabrielle G. M., Tysma, Odette H. M., Bergen, Cees A. M., Kester, Michel G. D., Ossendorp, Ferry, van Veelen, Peter A., Keymeulen, Bart, Pipeleers, Danny, Drijfhout, Jan W., Roep, Bart O.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317949/
https://ncbi.nlm.nih.gov/pubmed/16339897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508621102
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