Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes

Type 1 diabetes is a T cell-mediated autoimmune disease, and insulin is an important target of the autoimmune response associated with β cell destruction. The mechanism of destruction is still unknown. Here, we provide evidence for CD8 T cell autoreactivity associated with recurrent autoimmunity and...

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Bibliografski detalji
Glavni autori: Pinkse, Gabrielle G. M., Tysma, Odette H. M., Bergen, Cees A. M., Kester, Michel G. D., Ossendorp, Ferry, van Veelen, Peter A., Keymeulen, Bart, Pipeleers, Danny, Drijfhout, Jan W., Roep, Bart O.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317949/
https://ncbi.nlm.nih.gov/pubmed/16339897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508621102
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