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Successful generation of primary virus-specific and anti-tumor T-cell responses from the naïve donor T-cell repertoire is determined by the balance between antigen-specific precursor T cells and regulatory T cells
BACKGROUND: One of the major challenges in allogeneic stem cell transplantation is to find a balance between the harmful induction of graft-versus-host disease and the beneficial graft-versus-leukemia and pathogen-specific immune responses. Adoptive transfer of in-vitro generated donor T cells with...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
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Ferrata Storti Foundation
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148915/ https://ncbi.nlm.nih.gov/pubmed/21546501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.039099 |
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