Arp2/3 Complex from Acanthamoeba Binds Profilin and Cross-links Actin Filaments

Por Mullins, R. Dyche, Kelleher, Joseph F., Xu, James, Pollard, Thomas D.
Publicado em 1998

RAS/MAPK activation drives resistance to Smo inhibition, metastasis and tumor evolution in Shh pathway-dependent tumors

Por Zhao, Xuesong, Ponomaryov, Tatyana, Ornell, Kimberly J., Zhou, Pengcheng, Dabral, Sukriti K., Pak, Ekaterina, Li, Wei, Atwood, Scott X., Whitson, Ramon J., Chang, Anne Lynn S., Li, Jiang, Oro, Anthony E., Chan, Jennifer A., Kelleher, Joseph F., Segal, Rosalind A.
Publicado no Cancer Res (2015)

Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities

Por Gruber-Filbin, Mariella, Dabral, Sukriti K., Pazyra-Murphy, Maria F., Ramkissoon, Shakti, Kung, Andrew L., Pak, Ekaterina, Chung, Jarom, Theisen, Matthew A., Sun, Yanping, Franchetti, Yoko, Sun, Yu, Shulman, David S., Redjal, Navid, Tabak, Barbara, Beroukhim, Rameen, Wang, Qi, Zhao, Jean, Dorsch, Marion, Buonamici, Silvia, Ligon, Keith L., Kelleher, Joseph F., Segal, Rosalind A.
Publicado em 2013

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Por Pan, Shifeng, Wu, Xu, Jiang, Jiqing, Gao, Wenqi, Wan, Yongqin, Cheng, Dai, Han, Dong, Liu, Jun, Englund, Nathan P., Wang, Yan, Peukert, Stefan, Miller-Moslin, Karen, Yuan, Jing, Guo, Ribo, Matsumoto, Melissa, Vattay, Anthony, Jiang, Yun, Tsao, Jeffrey, Sun, Fangxian, Pferdekamper, AnneMarie C., Dodd, Stephanie, Tuntland, Tove, Maniara, Wieslawa, Kelleher, Joseph F., Yao, Yung-mae, Warmuth, Markus, Williams, Juliet, Dorsch, Marion
Publicado em 2010

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Por Buonamici, Silvia, Williams, Juliet, Morrissey, Michael, Wang, Anlai, Guo, Ribo, Vattay, Anthony, Hsiao, Kathy, Yuan, Jing, Green, John, Ospina, Beatrice, Yu, Qunyan, Ostrom, Lance, Fordjour, Paul, Anderson, Dustin L., Monahan, John E., Kelleher, Joseph F., Peukert, Stefan, Pan, Shifeng, Wu, Xu, Maira, Sauveur-Michel, Garcia-Echeverria, Carlos, Briggs, Kimberly J., Watkins, D. Neil, Yao, Yung-mae, Lengauer, Christoph, Warmuth, Markus, Sellers, William R., Dorsch, Marion
Publicado em 2010

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

Por Jagani, Zainab, Mora-Blanco, E Lorena, Sansam, Courtney G, McKenna, Elizabeth S, Wilson, Boris, Chen, Dongshu, Klekota, Justin, Tamayo, Pablo, Nguyen, Phuong T L, Tolstorukov, Michael, Park, Peter J, Cho, Yoon-Jae, Hsiao, Kathy, Buonamici, Silvia, Pomeroy, Scott L, Mesirov, Jill P, Ruffner, Heinz, Bouwmeester, Tewis, Luchansky, Sarah J, Murtie, Joshua, Kelleher, Joseph F, Warmuth, Markus, Sellers, William R, Roberts, Charles W M, Dorsch, Marion
Publicado em 2010