Microwave-assisted Protection of Primary Amines as 2,5-Dimethylpyrroles and Their Orthogonal Deprotection

Por Walia, Amit, Kang, Soosung, Silverman, Richard B
Publicado em 2013

Development Of Nitric Oxide Synthase Inhibitors for Neurodegeneration and Neuropathic Pain

Por Mukherjee, Paramita, Cinelli, Maris A., Kang, Soosung, Silverman, Richard B.
Publicado em 2014

Electrostatic control of isoform selective inhibitor binding in nitric oxide synthase

Por Li, Huiying, Wang, Heng-Yen, Kang, Soosung, Silverman, Richard B., Poulos, Thomas L.
Publicado no Biochemistry (2016)

Structure-Activity Relationship of N,N′-Disubstituted Pyrimidinetriones as Ca(V)1.3 Calcium Channel-Selective Antagonists for Parkinson’s Disease

Por Kang, Soosung, Cooper, Garry, Fernandez Dunne, Sara, Luan, Chi-Hao, Surmeier, D. James, Silverman, Richard B.
Publicado no J Med Chem (2013)

Structural and biological studies on bacterial nitric oxide synthase inhibitors

Por Holden, Jeffrey K., Li, Huiying, Jing, Qing, Kang, Soosung, Richo, Jerry, Silverman, Richard B., Poulos, Thomas L.
Publicado em 2013

Synthesis of Mevalonate- and Fluorinated Mevalonate Prodrugs and Their in vitro Human Plasma Stability

Por Kang, Soosung, Watanabe, Mizuki, Jacobs, JC, Yamaguchi, Masaya, Dahesh, Samira, Nizet, Victor, Leyh, Thomas S., Silverman, Richard B.
Publicado no Eur J Med Chem (2014)

2-Aminopyridines with a Truncated Side Chain to Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity

Por Kang, Soosung, Li, Huiying, Tang, Wei, Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Publicado no J Med Chem (2015)

Nitric Oxide Synthase Inhibitors That Interact with Both Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity

Por Kang, Soosung, Tang, Wei, Li, Huiying, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Publicado em 2014

Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2

Por St. John, Sarah E., Jensen, Katherine C., Kang, SooSung, Chen, Yafang, Calamini, Barbara, Mesecar, Andrew D., Lipton, Mark A.
Publicado em 2013

Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase

Por Cinelli, Maris A., Li, Huiying, Pensa, Anthony V., Kang, Soosung, Roman, Linda J., Martásek, Pavel, Poulos, Thomas L., Silverman, Richard B.
Publicado no J Med Chem (2015)

Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase

Por Cinelli, Maris A., Li, Huiying, Pensa, Anthony V., Kang, Soosung, Roman, Linda J., Martásek, Pavel, Poulos, Thomas L., Silverman, Richard B.
Publicado no J Med Chem (2016)

The Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme–Inhibitor Interactions in Nitric Oxide Synthases

Por Li, Huiying, Jamal, Joumana, Delker, Silvia, Plaza, Carla, Ji, Haitao, Jing, Qing, Huang, He, Kang, Soosung, Silverman, Richard B., Poulos, Thomas L.
Publicado em 2014

Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase

Por Holden, Jeffrey K., Dejam, Dillon, Lewis, Matthew C., Huang, He, Kang, Soosung, Jing, Qing, Xue, Fengtian, Silverman, Richard B., Poulos, Thomas L.
Publicado no Biochemistry (2015)

Structure-Based Design of Bacterial Nitric Oxide Synthase Inhibitors

Por Holden, Jeffrey K., Kang, Soosung, Hollingsworth, Scott A., Li, Huiying, Lim, Nathan, Chen, Steven, Huang, He, Xue, Fengtian, Tang, Wei, Silverman, Richard B., Poulos, Thomas L.
Publicado no J Med Chem (2014)

Nitric Oxide Synthase as a Target for Methicillin Resistant Staphylococcus aureus

Por Holden, Jeffrey K., Kang, Soosung, Beasley, Federico C., Cinelli, Maris A., Li, Huiying, Roy, Saurabh G., Dejam, Dillon, Edinger, Aimee L., Nizet, Victor, Silverman, Richard B., Poulos, Thomas L.
Publicado no Chem Biol (2015)

Regulation of aldosterone secretion by Ca(v)1.3

Por Xie, Catherine B., Haris Shaikh, Lalarukh, Garg, Sumedha, Tanriver, Gizem, Teo, Ada E. D., Zhou, Junhua, Maniero, Carmela, Zhao, Wanfeng, Kang, Soosung, Silverman, Richard B., Azizan, Elena A. B., Brown, Morris J.
Publicado no Sci Rep (2016)

Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease

Por Teixeira-Castro, Andreia, Jalles, Ana, Esteves, Sofia, Kang, Soosung, da Silva Santos, Liliana, Silva-Fernandes, Anabela, Neto, Mário F., Brielmann, Renée M., Bessa, Carlos, Duarte-Silva, Sara, Miranda, Adriana, Oliveira, Stéphanie, Neves-Carvalho, Andreia, Bessa, João, Summavielle, Teresa, Silverman, Richard B., Oliveira, Pedro, Morimoto, Richard I., Maciel, Patrícia
Publicado no Brain (2015)