Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase

Nitric oxide generated by bacterial nitric oxide synthase (NOS) increases the susceptibility of Gram-positive pathogens Staphylococcus aureus and Bacillus anthracis to oxidative stress, including antibiotic-induced oxidative stress. Not surprisingly, NOS inhibitors also improve the effectiveness of...

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Publicado en:Biochemistry
Main Authors: Holden, Jeffrey K., Dejam, Dillon, Lewis, Matthew C., Huang, He, Kang, Soosung, Jing, Qing, Xue, Fengtian, Silverman, Richard B., Poulos, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860011/
https://ncbi.nlm.nih.gov/pubmed/26062720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00431
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