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Nitric Oxide Synthase Inhibitors That Interact with Both Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity
[Image: see text] Overproduction of NO by nNOS is implicated in the pathogenesis of diverse neuronal disorders. Since NO signaling is involved in diverse physiological functions, selective inhibition of nNOS over other isoforms is essential to minimize side effects. A series of α-amino functionalize...
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| Hoofdauteurs: | , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical
Society
2014
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4032192/ https://ncbi.nlm.nih.gov/pubmed/24758147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5004182 |
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