IKK/NF-κB signaling: balancing life and death – a new approach to cancer therapy

Por Luo, Jun-Li, Kamata, Hideaki, Karin, Michael
Publicado em 2005

AMP-activated Protein Kinase Activation Increases Phosphorylation of Glycogen Synthase Kinase 3β and Thereby Reduces cAMP-responsive Element Transcriptional Activity and Phosphoe...

Por Horike, Nanao, Sakoda, Hideyuki, Kushiyama, Akifumi, Ono, Hiraku, Fujishiro, Midori, Kamata, Hideaki, Nishiyama, Koichi, Uchijima, Yasunobu, Kurihara, Yukiko, Kurihara, Hiroki, Asano, Tomoichiro
Publicado em 2008

Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice

Por Iwashita, Misaki, Nakatsu, Yusuke, Sakoda, Hideyuki, Fujishiro, Midori, Kushiyama, Akifumi, Fukushima, Toshiaki, Kumamoto, Sonoko, Shinjo, Takanori, Kamata, Hideaki, Nishimura, Fusanori, Asano, Tomoichiro
Publicado em 2013

Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus

Por Qiang, Shirong, Nakatsu, Yusuke, Seno, Yasuyuki, Fujishiro, Midori, Sakoda, Hideyuki, Kushiyama, Akifumi, Mori, Keiichi, Matsunaga, Yasuka, Yamamotoya, Takeshi, Kamata, Hideaki, Asano, Tomoichiro
Publicado no Diabetol Metab Syndr (2015)

Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines

Por Kanaoka, Ryuhei, Kushiyama, Akifumi, Seno, Yasuyuki, Nakatsu, Yusuke, Matsunaga, Yasuka, Fukushima, Toshiaki, Tsuchiya, Yoshihiro, Sakoda, Hideyuki, Fujishiro, Midori, Yamamotoya, Takeshi, Kamata, Hideaki, Matsubara, Akio, Asano, Tomoichiro
Publicado no PLoS One (2015)

On–off system for PI3-kinase–Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)

Por Numajiri, Naoki, Takasawa, Kumi, Nishiya, Tadashi, Tanaka, Hirotaka, Ohno, Kazuki, Hayakawa, Wataru, Asada, Mariko, Matsuda, Hiromi, Azumi, Kaoru, Kamata, Hideaki, Nakamura, Tomohiro, Hara, Hideaki, Minami, Masabumi, Lipton, Stuart A., Uehara, Takashi
Publicado em 2011

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis

Por Matsunaga, Yasuka, Nakatsu, Yusuke, Fukushima, Toshiaki, Okubo, Hirofumi, Iwashita, Misaki, Sakoda, Hideyuki, Fujishiro, Midori, Yamamotoya, Takeshi, Kushiyama, Akifumi, Takahashi, Shin-ichiro, Tsuchiya, Yoshihiro, Kamata, Hideaki, Tokunaga, Fuminori, Iwai, Kazuhiro, Asano, Tomoichiro
Publicado no Mediators Inflamm (2015)

HECT‐Type Ubiquitin E3 Ligase ITCH Interacts With Thioredoxin‐Interacting Protein and Ameliorates Reactive Oxygen Species–Induced Cardiotoxicity

Por Otaki, Yoichiro, Takahashi, Hiroki, Watanabe, Tetsu, Funayama, Akira, Netsu, Shunsuke, Honda, Yuki, Narumi, Taro, Kadowaki, Shinpei, Hasegawa, Hiromasa, Honda, Shintaro, Arimoto, Takanori, Shishido, Tetsuro, Miyamoto, Takuya, Kamata, Hideaki, Nakajima, Osamu, Kubota, Isao
Publicado no J Am Heart Assoc (2016)

Prolyl Isomerase Pin1 Negatively Regulates AMP-activated Protein Kinase (AMPK) by Associating with the CBS Domain in the γ Subunit

Por Nakatsu, Yusuke, Iwashita, Misaki, Sakoda, Hideyuki, Ono, Hiraku, Nagata, Kengo, Matsunaga, Yasuka, Fukushima, Toshiaki, Fujishiro, Midori, Kushiyama, Akifumi, Kamata, Hideaki, Takahashi, Shin-Ichiro, Katagiri, Hideki, Honda, Hiroaki, Kiyonari, Hiroshi, Uchida, Takafumi, Asano, Tomoichiro
Publicado no J Biol Chem (2015)

Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice

Por Okubo, Hirofumi, Kushiyama, Akifumi, Sakoda, Hideyuki, Nakatsu, Yusuke, Iizuka, Masaki, Taki, Naoyuki, Fujishiro, Midori, Fukushima, Toshiaki, Kamata, Hideaki, Nagamachi, Akiko, Inaba, Toshiya, Nishimura, Fusanori, Katagiri, Hideki, Asahara, Takashi, Yoshida, Yasuto, Chonan, Osamu, Encinas, Jeffery, Asano, Tomoichiro
Publicado no Sci Rep (2016)

Pin1 Associates with and Induces Translocation of CRTC2 to the Cytosol, Thereby Suppressing cAMP-responsive Element Transcriptional Activity

Por Nakatsu, Yusuke, Sakoda, Hideyuki, Kushiyama, Akifumi, Ono, Hiraku, Fujishiro, Midori, Horike, Nanao, Yoneda, Masayasu, Ohno, Haruya, Tsuchiya, Yoshihiro, Kamata, Hideaki, Tahara, Hidetoshi, Isobe, Toshiaki, Nishimura, Fusanori, Katagiri, Hideki, Oka, Yoshitomo, Fukushima, Toshiaki, Takahashi, Shin-Ichiro, Kurihara, Hiroki, Uchida, Takafumi, Asano, Tomoichiro
Publicado em 2010

Par14 Protein Associates with Insulin Receptor Substrate 1 (IRS-1), Thereby Enhancing Insulin-induced IRS-1 Phosphorylation and Metabolic Actions

Por Zhang, Jun, Nakatsu, Yusuke, Shinjo, Takanori, Guo, Ying, Sakoda, Hideyuki, Yamamotoya, Takeshi, Otani, Yuichiro, Okubo, Hirofumi, Kushiyama, Akifumi, Fujishiro, Midori, Fukushima, Toshiaki, Tsuchiya, Yoshihiro, Kamata, Hideaki, Iwashita, Misaki, Nishimura, Fusanori, Katagiri, Hideki, Takahashi, Shin-ichiro, Kurihara, Hiroki, Uchida, Takafumi, Asano, Tomoichiro
Publicado em 2013

Role of Pin1 Protein in the Pathogenesis of Nonalcoholic Steatohepatitis in a Rodent Model

Por Nakatsu, Yusuke, Otani, Yuichiro, Sakoda, Hideyuki, Zhang, Jun, Guo, Ying, Okubo, Hirofumi, Kushiyama, Akifumi, Fujishiro, Midori, Kikuch, Takako, Fukushima, Toshiaki, Ohno, Haruya, Tsuchiya, Yoshihiro, Kamata, Hideaki, Nagamachi, Akiko, Inaba, Toshiya, Nishimura, Fusanori, Katagiri, Hideki, Takahashi, Shin-ichiro, Kurihara, Hiroki, Uchida, Takafumi, Asano, Tomoichiro
Publicado em 2012

Peptidyl-prolyl Cis/Trans Isomerase NIMA-interacting 1 Associates with Insulin Receptor Substrate-1 and Enhances Insulin Actions and Adipogenesis

Por Nakatsu, Yusuke, Sakoda, Hideyuki, Kushiyama, Akifumi, Zhang, Jun, Ono, Hiraku, Fujishiro, Midori, Kikuchi, Takako, Fukushima, Toshiaki, Yoneda, Masayasu, Ohno, Haruya, Horike, Nanao, Kanna, Machi, Tsuchiya, Yoshihiro, Kamata, Hideaki, Nishimura, Fusanori, Isobe, Toshiaki, Ogihara, Takehide, Katagiri, Hideki, Oka, Yoshitomo, Takahashi, Shin-ichiro, Kurihara, Hiroki, Uchida, Takafumi, Asano, Tomoichiro
Publicado em 2011