Role of Pin1 Protein in the Pathogenesis of Nonalcoholic Steatohepatitis in a Rodent Model

Nonalcoholic steatohepatitis (NASH) is a disorder characterized by simultaneous fat accumulation and chronic inflammation in the liver. In this study, Pin1 expression was revealed to be markedly increased in the livers of mice with methionine choline-deficient (MCD) diet-induced NASH, a rodent model...

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Autores principales: Nakatsu, Yusuke, Otani, Yuichiro, Sakoda, Hideyuki, Zhang, Jun, Guo, Ying, Okubo, Hirofumi, Kushiyama, Akifumi, Fujishiro, Midori, Kikuch, Takako, Fukushima, Toshiaki, Ohno, Haruya, Tsuchiya, Yoshihiro, Kamata, Hideaki, Nagamachi, Akiko, Inaba, Toshiya, Nishimura, Fusanori, Katagiri, Hideki, Takahashi, Shin-ichiro, Kurihara, Hiroki, Uchida, Takafumi, Asano, Tomoichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531766/
https://ncbi.nlm.nih.gov/pubmed/23112047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397133
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