Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus

Por Qiang, Shirong, Nakatsu, Yusuke, Seno, Yasuyuki, Fujishiro, Midori, Sakoda, Hideyuki, Kushiyama, Akifumi, Mori, Keiichi, Matsunaga, Yasuka, Yamamotoya, Takeshi, Kamata, Hideaki, Asano, Tomoichiro
Publicado no Diabetol Metab Syndr (2015)

Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations

Por Nakatsu, Yusuke, Matsunaga, Yasuka, Yamamotoya, Takeshi, Ueda, Koji, Inoue, Yuki, Mori, Keiichi, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Kushiyama, Akifumi, Asano, Tomoichiro
Publicado no Int J Mol Sci (2016)

Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis

Por Kushiyama, Akifumi, Nakatsu, Yusuke, Matsunaga, Yasuka, Yamamotoya, Takeshi, Mori, Keiichi, Ueda, Koji, Inoue, Yuki, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Asano, Tomoichiro
Publicado no Mediators Inflamm (2016)

Reduced SHARPIN and LUBAC Formation May Contribute to CCl(4)- or Acetaminophen-Induced Liver Cirrhosis in Mice

Por Yamamotoya, Takeshi, Nakatsu, Yusuke, Matsunaga, Yasuka, Fukushima, Toshiaki, Yamazaki, Hiroki, Kaneko, Sunao, Fujishiro, Midori, Kikuchi, Takako, Kushiyama, Akifumi, Tokunaga, Fuminori, Asano, Tomoichiro, Sakoda, Hideyuki
Publicado no Int J Mol Sci (2017)

Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines

Por Kanaoka, Ryuhei, Kushiyama, Akifumi, Seno, Yasuyuki, Nakatsu, Yusuke, Matsunaga, Yasuka, Fukushima, Toshiaki, Tsuchiya, Yoshihiro, Sakoda, Hideyuki, Fujishiro, Midori, Yamamotoya, Takeshi, Kamata, Hideaki, Matsubara, Akio, Asano, Tomoichiro
Publicado no PLoS One (2015)

Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity

Por Yamamotoya, Takeshi, Nakatsu, Yusuke, Kushiyama, Akifumi, Matsunaga, Yasuka, Ueda, Koji, Inoue, Yuki, Inoue, Masa-Ki, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Kiyonari, Hiroshi, Ishihara, Hisamitsu, Asano, Tomoichiro
Publicado no Sci Rep (2017)

The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion

Por Nakatsu, Yusuke, Mori, Keiichi, Matsunaga, Yasuka, Yamamotoya, Takeshi, Ueda, Koji, Inoue, Yuki, Mitsuzaki-Miyoshi, Keiko, Sakoda, Hideyuki, Fujishiro, Midori, Yamaguchi, Suguru, Kushiyama, Akifumi, Ono, Hiraku, Ishihara, Hisamitsu, Asano, Tomoichiro
Publicado no J Biol Chem (2017)

The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic A...

Por Nakatsu, Yusuke, Kokubo, Hiroki, Bumdelger, Batmunkh, Yoshizumi, Masao, Yamamotoya, Takeshi, Matsunaga, Yasuka, Ueda, Koji, Inoue, Yuki, Inoue, Masa-Ki, Fujishiro, Midori, Kushiyama, Akifumi, Ono, Hiraku, Sakoda, Hideyuki, Asano, Tomoichiro
Publicado no Int J Mol Sci (2017)

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis

Por Matsunaga, Yasuka, Nakatsu, Yusuke, Fukushima, Toshiaki, Okubo, Hirofumi, Iwashita, Misaki, Sakoda, Hideyuki, Fujishiro, Midori, Yamamotoya, Takeshi, Kushiyama, Akifumi, Takahashi, Shin-ichiro, Tsuchiya, Yoshihiro, Kamata, Hideaki, Tokunaga, Fuminori, Iwai, Kazuhiro, Asano, Tomoichiro
Publicado no Mediators Inflamm (2015)

Prolyl Isomerase Pin1 Negatively Regulates AMP-activated Protein Kinase (AMPK) by Associating with the CBS Domain in the γ Subunit

Por Nakatsu, Yusuke, Iwashita, Misaki, Sakoda, Hideyuki, Ono, Hiraku, Nagata, Kengo, Matsunaga, Yasuka, Fukushima, Toshiaki, Fujishiro, Midori, Kushiyama, Akifumi, Kamata, Hideaki, Takahashi, Shin-Ichiro, Katagiri, Hideki, Honda, Hiroaki, Kiyonari, Hiroshi, Uchida, Takafumi, Asano, Tomoichiro
Publicado no J Biol Chem (2015)