The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice

Recent clinical studies have revealed the treatment of diabetic patients with sodium glucose co-transporter2 (SGLT2) inhibitors to reduce the incidence of cardiovascular events. Using nicotinamide and streptozotocin (NA/STZ) -treated ApoE KO mice, we investigated the effects of short-term (seven day...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Nakatsu, Yusuke, Kokubo, Hiroki, Bumdelger, Batmunkh, Yoshizumi, Masao, Yamamotoya, Takeshi, Matsunaga, Yasuka, Ueda, Koji, Inoue, Yuki, Inoue, Masa-Ki, Fujishiro, Midori, Kushiyama, Akifumi, Ono, Hiraku, Sakoda, Hideyuki, Asano, Tomoichiro
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578094/
https://ncbi.nlm.nih.gov/pubmed/28777298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081704
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