Pin1 Plays Essential Roles in NASH Development by Modulating Multiple Target Proteins

Pin1 is one of the three known prolyl-isomerase types and its hepatic expression level is markedly enhanced in the obese state. Pin1 plays critical roles in favoring the exacerbation of both lipid accumulation and fibrotic change accompanying inflammation. Indeed, Pin1-deficient mice are highly resi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Inoue, Masa-Ki, Nakatsu, Yusuke, Yamamotoya, Takeshi, Hasei, Shun, Kanamoto, Mayu, Naitou, Miki, Matsunaga, Yasuka, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Kushiyama, Akifumi, Asano, Tomoichiro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952946/
https://ncbi.nlm.nih.gov/pubmed/31795496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121545
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker