Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells

Carnosic acid (CA), carnosol (CL) and rosmarinic acid (RA), components of the herb rosemary, reportedly exert favorable metabolic actions. This study showed that both CA and CL, but not RA, induce significant phosphorylation of AMP-dependent kinase (AMPK) and its downstream acetyl-CoA carboxylase 1...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hasei, Shun, Yamamotoya, Takeshi, Nakatsu, Yusuke, Ohata, Yukino, Itoga, Shota, Nonaka, Yuji, Matsunaga, Yasuka, Sakoda, Hideyuki, Fujishiro, Midori, Kushiyama, Akifumi, Asano, Tomoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070802/
https://ncbi.nlm.nih.gov/pubmed/33919842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084040
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