Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice

BACKGROUND: Recently, clinical studies have shown the protective effects of sodium glucose co-transporter2 (SGLT2) inhibitors against progression of diabetic nephropathy, but the underlying molecular mechanisms remain unclear. METHODS: Diabetic mice were prepared by injecting nicotinamide and strept...

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Библиографические подробности
Опубликовано в: :Diabetol Metab Syndr
Главные авторы: Inoue, Masa-Ki, Matsunaga, Yasuka, Nakatsu, Yusuke, Yamamotoya, Takeshi, Ueda, Koji, Kushiyama, Akifumi, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Iwashita, Misaki, Sano, Tomomi, Nishimura, Fusanori, Morii, Kenichi, Sasaki, Kensuke, Masaki, Takao, Asano, Tomoichiro
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647324/
https://ncbi.nlm.nih.gov/pubmed/31367234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-019-0454-6
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