High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice

BACKGROUND: DPP-4 inhibitors reportedly exert effects on both alpha and beta cells, and promote the proliferation and survival of beta cells. We investigated the effects of anagliptin on structurally-impaired islets of Langerhans in streptozotocin (STZ)-treated mice, fed either a normal or a high-fa...

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Detalhes bibliográficos
Publicado no:Diabetol Metab Syndr
Main Authors: Shinjo, Takanori, Nakatsu, Yusuke, Iwashita, Misaki, Sano, Tomomi, Sakoda, Hideyuki, Ishihara, Hisamitsu, Kushiyama, Akifumi, Fujishiro, Midori, Nishimura, Fusanori, Asano, Tomoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475295/
https://ncbi.nlm.nih.gov/pubmed/26097511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-015-0047-y
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