Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come

Por Yingchoncharoen, Phatsapong, Kalinowski, Danuta S., Richardson, Des R.
Publicado no Pharmacol Rev (2016)

Unraveling the mysteries of serum albumin—more than just a serum protein

Por Merlot, Angelica M., Kalinowski, Danuta S., Richardson, Des R.
Publicado em 2014

Effect of the Piperazine Unit and Metal-Binding Site Position on the Solubility and Anti-Proliferative Activity of Ruthenium(II)- and Osmium(II)- Arene Complexes of Isomeric Indolo...

Por Filak, Lukas K., Kalinowski, Danuta S., Bauer, Theresa J., Richardson, Des R., Arion, Vladimir B.
Publicado em 2014

Targeting cancer by binding iron: Dissecting cellular signaling pathways

Por Lui, Goldie Y.L., Kovacevic, Zaklina, Richardson, Vera, Merlot, Angelica M., Kalinowski, Danuta S., Richardson, Des R.
Publicado no Oncotarget (2015)

Nitrogen Monoxide (NO) Storage and Transport by Dinitrosyl-Dithiol-Iron Complexes: Long-lived NO That Is Trafficked by Interacting Proteins

Por Suryo Rahmanto, Yohan, Kalinowski, Danuta S., Lane, Darius J. R., Lok, Hiu Chuen, Richardson, Vera, Richardson, Des R.
Publicado em 2012

The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms

Por Guo, Zhu-Ling, Richardson, Des R., Kalinowski, Danuta S., Kovacevic, Zaklina, Tan-Un, Kian Cheng, Chan, Godfrey Chi-Fung
Publicado no J Hematol Oncol (2016)

The Metastasis Suppressor, N-myc Downstream-regulated Gene 1 (NDRG1), Inhibits Stress-induced Autophagy in Cancer Cells

Por Sahni, Sumit, Bae, Dong-Hun, Lane, Darius J. R., Kovacevic, Zaklina, Kalinowski, Danuta S., Jansson, Patric J., Richardson, Des R.
Publicado em 2014

The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways

Por Kovacevic, Zaklina, Menezes, Sharleen V., Sahni, Sumit, Kalinowski, Danuta S., Bae, Dong-Hun, Lane, Darius J. R., Richardson, Des R.
Publicado no J Biol Chem (2016)

Letter to the Editor: “Analysis of the Interaction of Dp44mT with Human Serum Albumin and Calf Thymus DNA Using Molecular Docking and Spectroscopic Techniques”

Por Merlot, Angelica M., Sahni, Sumit, Lane, Darius J. R., Richardson, Vera, Huang, Michael L. H., Kalinowski, Danuta S., Richardson, Des R.
Publicado no Int J Mol Sci (2016)

Nitric Oxide Storage and Transport in Cells Are Mediated by Glutathione S-Transferase P1-1 and Multidrug Resistance Protein 1 via Dinitrosyl Iron Complexes

Por Lok, Hiu Chuen, Rahmanto, Yohan Suryo, Hawkins, Clare L., Kalinowski, Danuta S., Morrow, Charles S., Townsend, Alan J., Ponka, Prem, Richardson, Des R.
Publicado em 2012

Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs

Por Potuckova, Eliska, Jansova, Hana, Machacek, Miloslav, Vavrova, Anna, Haskova, Pavlina, Tichotova, Lucie, Richardson, Vera, Kalinowski, Danuta S., Richardson, Des R., Simunek, Tomas
Publicado em 2014

Anti-Plasmodial Activity of Aroylhydrazone and Thiosemicarbazone Iron Chelators: Effect on Erythrocyte Membrane Integrity, Parasite Development and the Intracellular Labile Iron Po...

Por Walcourt, Asikiya, Kurantsin-Mills, Joseph, Kwagyan, John, Adenuga, Babafemi B., Kalinowski, Danuta S., Lovejoy, David B., Lane, Darius J. R., Richardson, Des R.
Publicado em 2013

Development of a Sensitive HPLC Method to Measure In-Vitro Permeability of E- and Z-Isomeric Forms of Thiosemicarbazones in Caco-2 Monolayers

Por Debebe, Zufan, Nekhai, Sergei, Ashenafi, Meseret, Lovejoy, David B., Kalinowski, Danuta S., Gordeuk, Victor R., Byrnes, W. Malcolm, Richardson, Des R., Karla, Pradeep K.
Publicado em 2012

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

Por Potůčková, Eliška, Roh, Jaroslav, Macháček, Miloslav, Sahni, Sumit, Stariat, Ján, Šesták, Vít, Jansová, Hana, Hašková, Pavlína, Jirkovská, Anna, Vávrová, Kateřina, Kovaříková, Petra, Kalinowski, Danuta S., Richardson, Des R., Šimůnek, Tomáš
Publicado no PLoS One (2015)

Iron Chelators of the Di-2-pyridylketone Thiosemicarbazone and 2-Benzoylpyridine Thiosemicarbazone Series Inhibit HIV-1 Transcription: Identification...

Por Debebe, Zufan, Ammosova, Tatyana, Breuer, Denitra, Lovejoy, David B., Kalinowski, Danuta S., Karla, Pradeep K., Kumar, Krishna, Jerebtsova, Marina, Ray, Patricio, Kashanchi, Fatah, Gordeuk, Victor R., Richardson, Des R., Nekhai, Sergei
Publicado em 2011

Exploring the Anti-Cancer Activity of Novel Thiosemicarbazones Generated through the Combination of Retro-Fragments: Dissection of Critical Structure-Activity Relationships

Por Serda, Maciej, Kalinowski, Danuta S., Rasko, Nathalie, Potůčková, Eliška, Mrozek-Wilczkiewicz, Anna, Musiol, Robert, Małecki, Jan G., Sajewicz, Mieczysław, Ratuszna, Alicja, Muchowicz, Angelika, Gołąb, Jakub, Šimůnek, Tomáš, Richardson, Des R., Polanski, Jaroslaw
Publicado em 2014

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead ag...

Por Sestak, Vit, Stariat, Jan, Cermanova, Jolana, Potuckova, Eliska, Chladek, Jaroslav, Roh, Jaroslav, Bures, Jan, Jansova, Hana, Prusa, Petr, Sterba, Martin, Micuda, Stanislav, Simunek, Tomas, Kalinowski, Danuta S., Richardson, Des R., Kovarikova, Petra
Publicado no Oncotarget (2015)

The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1

Por Liu, Wensheng, Yue, Fei, Zheng, Minhua, Merlot, Angelica, Bae, Dong-Hun, Huang, Michael, Lane, Darius, Jansson, Patric, Liu, Goldie Yuan Lam, Richardson, Vera, Sahni, Sumit, Kalinowski, Danuta, Kovacevic, Zaklina, Richardson, Des. R.
Publicado no Oncotarget (2015)

Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells

Por Merlot, Angelica M., Sahni, Sumit, Lane, Darius J.R., Fordham, Ashleigh M., Pantarat, Namfon, Hibbs, David E., Richardson, Vera, Doddareddy, Munikumar R., Ong, Jennifer A., Huang, Michael L.H., Richardson, Des R., Kalinowski, Danuta S.
Publicado no Oncotarget (2015)

The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets

Por Liu, Wensheng, Kovacevic, Zaklina, Peng, Zhihai, Jin, Runsen, Wang, Puxiongzhi, Yue, Fei, Zheng, Minhua, Huang, Michael L-H., Jansson, Patric J., Richardson, Vera, Kalinowski, Danuta S., Lane, Darius J.R., Merlot, Angelica M., Sahni, Sumit, Richardson, Des R.
Publicado no Oncotarget (2015)