Pharmacy Practice and Education in the Czech Republic †

Por Nachtigal, Petr, Šimůnek, Tomáš, Atkinson, Jeffrey
Publicado no Pharmacy (Basel) (2017)

Oxidative Stress, Redox Signaling, and Metal Chelation in Anthracycline Cardiotoxicity and Pharmacological Cardioprotection

Por Štěrba, Martin, Popelová, Olga, Vávrová, Anna, Jirkovský, Eduard, Kovaříková, Petra, Geršl, Vladimír, Šimůnek, Tomáš
Publicado em 2013

Catalytic Inhibitors of Topoisomerase II Differently Modulate the Toxicity of Anthracyclines in Cardiac and Cancer Cells

Por Vavrova, Anna, Jansova, Hana, Mackova, Eliska, Machacek, Miloslav, Haskova, Pavlina, Tichotova, Lucie, Sterba, Martin, Simunek, Tomas
Publicado em 2013

UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study

Por Reimerová, Petra, Jirkovská, Anna, Piskáčková, Hana Bavlovič, Karabanovich, Galina, Roh, Jaroslav, Šimůnek, Tomáš, Štěrbová-Kovaříková, Petra
Publicado no Sci Rep (2019)

Molecular Remodeling of Left and Right Ventricular Myocardium in Chronic Anthracycline Cardiotoxicity and Post-Treatment Follow Up

Por Lenčová-Popelová, Olga, Jirkovský, Eduard, Mazurová, Yvona, Lenčo, Juraj, Adamcová, Michaela, Šimůnek, Tomáš, Geršl, Vladimír, Štěrba, Martin
Publicado em 2014

Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury

Por Hašková, Pavlína, Jansová, Hana, Bureš, Jan, Macháček, Miloslav, Jirkovská, Anna, Franz, Katherine J., Kovaříková, Petra, Šimůnek, Tomáš
Publicado no Toxicology (2016)

Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury

Por Jansová, Hana, Macháček, Miloslav, Wang, Qin, Hašková, Pavlína, Jirkovská, Anna, Potůčková, Eliška, Kielar, Filip, Franz, Katherine J., Šimůnek, Tomáš
Publicado no Free Radic Biol Med (2014)

Binding of an amphiphilic phthalocyanine to pre-formed liposomes confers light-triggered cargo release

Por Macháček, Miloslav, Carter, Kevin A, Kostelanský, Filip, Miranda, Dyego, Seffouh, Amal, Ortega, Joaquin, Šimůnek, Tomáš, Zimčík, Petr, Lovell, Jonathan F
Publicado no J Mater Chem B (2018)

Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs

Por Potuckova, Eliska, Jansova, Hana, Machacek, Miloslav, Vavrova, Anna, Haskova, Pavlina, Tichotova, Lucie, Richardson, Vera, Kalinowski, Danuta S., Richardson, Des R., Simunek, Tomas
Publicado em 2014

Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products

Por Jansová, Hana, Bureš, Jan, Macháček, Miloslav, Hašková, Pavlína, Jirkovská, Anna, Roh, Jaroslav, Wang, Qin, Franz, Katherine J., Kovaříková, Petra, Šimůnek, Tomáš
Publicado no Toxicology (2016)

LC-UV/MS methods for the analysis of prochelator - boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)

Por Bureš, Jan, Jansová, Hana, Stariat, Ján, Filipský, Tomáš, Mladěnka, Přemysl, Šimůnek, Tomáš, Kučera, Radim, Klimeš, Jiří, Wang, Qin, Franz, Katherine J., Kovaříková, Petra
Publicado no J Pharm Biomed Anal (2014)

Protective Effects of D-Penicillamine on Catecholamine-Induced Myocardial Injury

Por Říha, Michal, Hašková, Pavlína, Martin, Jan, Filipský, Tomáš, Váňová, Kateřina, Vávrová, Jaroslava, Holečková, Magdalena, Homola, Pavel, Vítek, Libor, Palicka, Vladimír, Šimůnek, Tomáš, Mladěnka, Přemysl
Publicado no Oxid Med Cell Longev (2016)

Intravenous rutin in rat exacerbates isoprenaline-induced cardiotoxicity likely due to intracellular oxidative stress

Por Filipský, Tomáš, Říha, Michal, Hašková, Pavlína, Pilařová, Veronika, Nováková, Lucie, Semecký, Vladimír, Vávrová, Jaroslava, Holečková, Magdaléna, Palicka, Vladimir, Šimůnek, Tomáš, Hrdina, Radomír, Mladěnka, Přemysl
Publicado no Redox Rep (2016)

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

Por Potůčková, Eliška, Roh, Jaroslav, Macháček, Miloslav, Sahni, Sumit, Stariat, Ján, Šesták, Vít, Jansová, Hana, Hašková, Pavlína, Jirkovská, Anna, Vávrová, Kateřina, Kovaříková, Petra, Kalinowski, Danuta S., Richardson, Des R., Šimůnek, Tomáš
Publicado no PLoS One (2015)

Exploring the Anti-Cancer Activity of Novel Thiosemicarbazones Generated through the Combination of Retro-Fragments: Dissection of Critical Structure-Activity Relationships

Por Serda, Maciej, Kalinowski, Danuta S., Rasko, Nathalie, Potůčková, Eliška, Mrozek-Wilczkiewicz, Anna, Musiol, Robert, Małecki, Jan G., Sajewicz, Mieczysław, Ratuszna, Alicja, Muchowicz, Angelika, Gołąb, Jakub, Šimůnek, Tomáš, Richardson, Des R., Polanski, Jaroslaw
Publicado em 2014

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead ag...

Por Sestak, Vit, Stariat, Jan, Cermanova, Jolana, Potuckova, Eliska, Chladek, Jaroslav, Roh, Jaroslav, Bures, Jan, Jansova, Hana, Prusa, Petr, Sterba, Martin, Micuda, Stanislav, Simunek, Tomas, Kalinowski, Danuta S., Richardson, Des R., Kovarikova, Petra
Publicado no Oncotarget (2015)

Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity

Por Bavlovič Piskáčková, Hana, Jansová, Hana, Kubeš, Jan, Karabanovich, Galina, Váňová, Nela, Kollárová-Brázdová, Petra, Melnikova, Iuliia, Jirkovská, Anna, Lenčová-Popelová, Olga, Chládek, Jaroslav, Roh, Jaroslav, Šimůnek, Tomáš, Štěrba, Martin, Štěrbová-Kovaříková, Petra
Publicado no Sci Rep (2021)

Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties

Por Potůčková, Eliška, Hrušková, Kateřina, Bureš, Jan, Kovaříková, Petra, Špirková, Iva A., Pravdíková, Kateřina, Kolbabová, Lucie, Hergeselová, Tereza, Hašková, Pavlína, Jansová, Hana, Macháček, Miloslav, Jirkovská, Anna, Richardson, Vera, Lane, Darius J. R., Kalinowski, Danuta S., Richardson, Des R., Vávrová, Kateřina, Šimůnek, Tomáš
Publicado no PLoS One (2014)