Oxidative Stress, Redox Signaling, and Metal Chelation in Anthracycline Cardiotoxicity and Pharmacological Cardioprotection

Por Štěrba, Martin, Popelová, Olga, Vávrová, Anna, Jirkovský, Eduard, Kovaříková, Petra, Geršl, Vladimír, Šimůnek, Tomáš
Publicado em 2013

Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury

Por Hašková, Pavlína, Jansová, Hana, Bureš, Jan, Macháček, Miloslav, Jirkovská, Anna, Franz, Katherine J., Kovaříková, Petra, Šimůnek, Tomáš
Publicado no Toxicology (2016)

Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products

Por Jansová, Hana, Bureš, Jan, Macháček, Miloslav, Hašková, Pavlína, Jirkovská, Anna, Roh, Jaroslav, Wang, Qin, Franz, Katherine J., Kovaříková, Petra, Šimůnek, Tomáš
Publicado no Toxicology (2016)

LC-UV/MS methods for the analysis of prochelator - boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)

Por Bureš, Jan, Jansová, Hana, Stariat, Ján, Filipský, Tomáš, Mladěnka, Přemysl, Šimůnek, Tomáš, Kučera, Radim, Klimeš, Jiří, Wang, Qin, Franz, Katherine J., Kovaříková, Petra
Publicado no J Pharm Biomed Anal (2014)

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

Por Potůčková, Eliška, Roh, Jaroslav, Macháček, Miloslav, Sahni, Sumit, Stariat, Ján, Šesták, Vít, Jansová, Hana, Hašková, Pavlína, Jirkovská, Anna, Vávrová, Kateřina, Kovaříková, Petra, Kalinowski, Danuta S., Richardson, Des R., Šimůnek, Tomáš
Publicado no PLoS One (2015)

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead ag...

Por Sestak, Vit, Stariat, Jan, Cermanova, Jolana, Potuckova, Eliska, Chladek, Jaroslav, Roh, Jaroslav, Bures, Jan, Jansova, Hana, Prusa, Petr, Sterba, Martin, Micuda, Stanislav, Simunek, Tomas, Kalinowski, Danuta S., Richardson, Des R., Kovarikova, Petra
Publicado no Oncotarget (2015)

Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties

Por Potůčková, Eliška, Hrušková, Kateřina, Bureš, Jan, Kovaříková, Petra, Špirková, Iva A., Pravdíková, Kateřina, Kolbabová, Lucie, Hergeselová, Tereza, Hašková, Pavlína, Jansová, Hana, Macháček, Miloslav, Jirkovská, Anna, Richardson, Vera, Lane, Darius J. R., Kalinowski, Danuta S., Richardson, Des R., Vávrová, Kateřina, Šimůnek, Tomáš
Publicado no PLoS One (2014)