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Anti-Plasmodial Activity of Aroylhydrazone and Thiosemicarbazone Iron Chelators: Effect on Erythrocyte Membrane Integrity, Parasite Development and the Intracellular Labile Iron Pool

Iron chelators inhibit the growth of the malaria parasite, Plasmodium falciparum, in culture and in animal and human studies. We previously reported the anti-plasmodial activity of the chelators, 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone (311), 2-hydroxy-1-naphthylaldehyde 4-methyl-3-thio...

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Detalhes bibliográficos
Main Authors: Walcourt, Asikiya, Kurantsin-Mills, Joseph, Kwagyan, John, Adenuga, Babafemi B., Kalinowski, Danuta S., Lovejoy, David B., Lane, Darius J. R., Richardson, Des R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838870/
https://ncbi.nlm.nih.gov/pubmed/24028863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2013.08.007
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