The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways

N-MYC downstream-regulated gene-1 (NDRG1) is a potent growth and metastasis suppressor that acts through its inhibitory effects on a wide variety of cellular signaling pathways, including the TGF-β pathway, protein kinase B (AKT)/PI3K pathway, RAS, etc. To investigate the hypothesis that its multipl...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Kovacevic, Zaklina, Menezes, Sharleen V., Sahni, Sumit, Kalinowski, Danuta S., Bae, Dong-Hun, Lane, Darius J. R., Richardson, Des R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714189/
https://ncbi.nlm.nih.gov/pubmed/26534963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.689653
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