Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling

The iron-regulated metastasis suppressor N-myc downstream-regulated gene 1 (NDRG1) has been shown to inhibit numerous oncogenic signaling pathways in cancer cells. Recent findings have demonstrated that NDRG1 inhibits the ErbB family of receptors, which function as key inducers of carcinogenesis. ND...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Menezes, Sharleen V., Sahni, Sumit, Kovacevic, Zaklina, Richardson, Des R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546018/
https://ncbi.nlm.nih.gov/pubmed/28615452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.776393
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