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N-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron Depletion

Iron is critical for cellular proliferation and its depletion leads to a suppression of both DNA synthesis and global translation. These observations suggest that iron depletion may trigger a cellular “stress response”. A canonical response of cells to stress is the formation of stress granules, whi...

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Autors principals: Lane, Darius J. R., Saletta, Federica, Rahmanto, Yohan Suryo, Kovacevic, Zaklina, Richardson, Des R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578820/
https://ncbi.nlm.nih.gov/pubmed/23437357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057273
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