Elevated exosomal secretion of miR-124-3p from spinal neurons positively associates with disease severity in ALS

le Yelick, Julia, Men, Yuqin, Jin, Shijie, Seo, Sabrina, Espejo-Porras, Francisco, Yang, Yongjie
Foilsithe in Exp Neurol (2020)

A Versatile Chemo-Enzymatic Conjugation Approach Yields Homogeneous and Highly Potent Antibody-Drug Conjugates

le Xu, Ying, Jin, Shijie, Zhao, Wenbin, Liu, Wenhui, Ding, Ding, Zhou, Jie, Chen, Shuqing
Foilsithe in Int J Mol Sci (2017)

Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity

le Mizuno, Tetsuya, Doi, Yukiko, Mizoguchi, Hiroyuki, Jin, Shijie, Noda, Mariko, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Suzumura, Akio
Foilsithe 2011

Interleukin-34 Restores Blood–Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells

le Jin, Shijie, Sonobe, Yoshifumi, Kawanokuchi, Jun, Horiuchi, Hiroshi, Cheng, Yi, Wang, Yue, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Foilsithe in PLoS One (2014)

TCR-mimic antibody-drug conjugates targeting intracellular tumor-specific mutant antigen KRAS G12V mutation

le Shen, Ying, Wei, Xiaoyue, Jin, Shijie, Wu, Yue, Zhao, Wenbin, Xu, Yingchun, Pan, Liqiang, Zhou, Zhan, Chen, Shuqing
Foilsithe in Asian J Pharm Sci (2020)

Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease

le Doi, Yukiko, Mizuno, Tetsuya, Maki, Yuki, Jin, Shijie, Mizoguchi, Hiroyuki, Ikeyama, Masayoshi, Doi, Minoru, Michikawa, Makoto, Takeuchi, Hideyuki, Suzumura, Akio
Foilsithe 2009

Fingolimod Phosphate Attenuates Oligomeric Amyloid β–Induced Neurotoxicity via Increased Brain-Derived Neurotrophic Factor Expression in Neurons

le Doi, Yukiko, Takeuchi, Hideyuki, Horiuchi, Hiroshi, Hanyu, Taketo, Kawanokuchi, Jun, Jin, Shijie, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Foilsithe 2013

Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes

le Wang, Yue, Jin, Shijie, Sonobe, Yoshifumi, Cheng, Yi, Horiuchi, Hiroshi, Parajuli, Bijay, Kawanokuchi, Jun, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Foilsithe 2014

Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS

le Watanabe, Seiji, Ilieva, Hristelina, Tamada, Hiromi, Nomura, Hanae, Komine, Okiru, Endo, Fumito, Jin, Shijie, Mancias, Pedro, Kiyama, Hiroshi, Yamanaka, Koji
Foilsithe in EMBO Mol Med (2016)

Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS

le Men, Yuqin, Yelick, Julia, Jin, Shijie, Tian, Yang, Chiang, Ming Sum R., Higashimori, Haruki, Brown, Eoin, Jarvis, Rachel, Yang, Yongjie
Foilsithe in Nat Commun (2019)

Interleukin-19 Abrogates Experimental Autoimmune Encephalomyelitis by Attenuating Antigen-Presenting Cell Activation

le Horiuchi, Hiroshi, Parajuli, Bijay, Komiya, Hiroyasu, Ogawa, Yuki, Jin, Shijie, Takahashi, Keita, Azuma, Yasu-Taka, Tanaka, Fumiaki, Suzumura, Akio, Takeuchi, Hideyuki
Foilsithe in Front Immunol (2021)

Interleukin-25 Expressed by Brain Capillary Endothelial Cells Maintains Blood-Brain Barrier Function in a Protein Kinase Cϵ-dependent Manner

le Sonobe, Yoshifumi, Takeuchi, Hideyuki, Kataoka, Kunio, Li, Hua, Jin, Shijie, Mimuro, Maya, Hashizume, Yoshio, Sano, Yasuteru, Kanda, Takashi, Mizuno, Tetsuya, Suzumura, Akio
Foilsithe 2009

Granulocyte-Colony Stimulating Factor Attenuates Oligomeric Amyloid β Neurotoxicity by Activation of Neprilysin

le Doi, Yukiko, Takeuchi, Hideyuki, Mizoguchi, Hiroyuki, Fukumoto, Kazuya, Horiuchi, Hiroshi, Jin, Shijie, Kawanokuchi, Jun, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Foilsithe 2014

Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cϵ-dependent manner.

le Sonobe, Yoshifumi, Takeuchi, Hideyuki, Kataoka, Kunio, Li, Hua, Jin, Shijie, Mimuro, Maya, Hashizume, Yoshio, Sano, Yasuteru, Kanda, Takashi, Mizuno, Tetsuya, Suzumura, Akio
Foilsithe in J Biol Chem (2016)

Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1−Akt signaling pathway

le Kohei Nishino, Seiji Watanabe, Jin Shijie, Yuri Murata, Kotaro Oiwa, Okiru Komine, Fumito Endo, Hitomi Tsuiji, Manabu Abe, Kenji Sakimura, Amit Mishra, Koji Yamanaka
Foilsithe 2019-07-01

Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population

le Wang, Jinyan, Takeuchi, Hideyuki, Sonobe, Yoshifumi, Jin, Shijie, Mizuno, Tetsuya, Miyakawa, Shin, Fujiwara, Masatoshi, Nakamura, Yoshikazu, Kato, Takuma, Muramatsu, Hisako, Muramatsu, Takashi, Suzumura, Akio
Foilsithe 2008

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes

le Komine, Okiru, Yamashita, Hirofumi, Fujimori-Tonou, Noriko, Koike, Masato, Jin, Shijie, Moriwaki, Yasuhiro, Endo, Fumito, Watanabe, Seiji, Uematsu, Satoshi, Akira, Shizuo, Uchiyama, Yasuo, Takahashi, Ryosuke, Misawa, Hidemi, Yamanaka, Koji
Foilsithe in Cell Death Differ (2018)

Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease

le Takeuchi, Hideyuki, Mizoguchi, Hiroyuki, Doi, Yukiko, Jin, Shijie, Noda, Mariko, Liang, Jianfeng, Li, Hua, Zhou, Yan, Mori, Rarami, Yasuoka, Satoko, Li, Endong, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Sato, Jun, Yamanaka, Koji, Sobue, Gen, Mizuno, Tetsuya, Suzumura, Akio
Foilsithe 2011