Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity

Microglia, macrophage-like resident immune cells in the brain, possess both neurotoxic and neuroprotective properties and have a critical role in the development of Alzheimer's disease (AD). We examined the function of Interleukin-34 (IL-34), a newly discovered cytokine, on microglia because it...

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Detalhes bibliográficos
Main Authors: Mizuno, Tetsuya, Doi, Yukiko, Mizoguchi, Hiroyuki, Jin, Shijie, Noda, Mariko, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Suzumura, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181379/
https://ncbi.nlm.nih.gov/pubmed/21872563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.011
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