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Elevated exosomal secretion of miR-124-3p from spinal neurons positively associates with disease severity in ALS

MicroRNAs (miRs) are powerful regulators of CNS development and diseases. Plasma and cerebrospinal fluid (CSF) miRs have recently been implicated as potential new sources for biomarker development. Previously we showed that miR-124–3p, an essential miR for neuronal identity, is highly abundant in ne...

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Bibliografiska uppgifter
I publikationen:Exp Neurol
Huvudupphovsmän: Yelick, Julia, Men, Yuqin, Jin, Shijie, Seo, Sabrina, Espejo-Porras, Francisco, Yang, Yongjie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502520/
https://ncbi.nlm.nih.gov/pubmed/32712030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113414
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