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Elevated exosomal secretion of miR-124-3p from spinal neurons positively associates with disease severity in ALS

MicroRNAs (miRs) are powerful regulators of CNS development and diseases. Plasma and cerebrospinal fluid (CSF) miRs have recently been implicated as potential new sources for biomarker development. Previously we showed that miR-124–3p, an essential miR for neuronal identity, is highly abundant in ne...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Neurol
Main Authors: Yelick, Julia, Men, Yuqin, Jin, Shijie, Seo, Sabrina, Espejo-Porras, Francisco, Yang, Yongjie
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502520/
https://ncbi.nlm.nih.gov/pubmed/32712030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113414
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