Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS

A homozygous mutation in the gene for sigma 1 receptor (Sig1R) is a cause of inherited juvenile amyotrophic lateral sclerosis (ALS16). Sig1R localizes to the mitochondria‐associated membrane (MAM), which is an interface of mitochondria and endoplasmic reticulum. However, the role of the MAM in ALS i...

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Detaylı Bibliyografya
Yayımlandı:EMBO Mol Med
Asıl Yazarlar: Watanabe, Seiji, Ilieva, Hristelina, Tamada, Hiromi, Nomura, Hanae, Komine, Okiru, Endo, Fumito, Jin, Shijie, Mancias, Pedro, Kiyama, Hiroshi, Yamanaka, Koji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167132/
https://ncbi.nlm.nih.gov/pubmed/27821430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606403
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